Query: NC_003413:128228 Pyrococcus furiosus DSM 3638, complete genome
Lineage: Pyrococcus furiosus; Pyrococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea
General Information: This strain was isolated from a shallow marine solfataric (volcanic area that gives off sulfuric gases) region at Vulcano Island, Italy. This organism is a strictly anaerobic, hyperthermophilic archaeon. Growth occurs at temperatures between 67 and 103 degrees C, with optimal growth at 100 degrees C and a pH of 7.0. This organism is highly motile due to a bundle of flagella.
Subject: NC_004310:1777721 Brucella suis 1330 chromosome I, complete sequence
Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.