Query: NC_003364:1081846 Pyrobaculum aerophilum str. IM2, complete genome Lineage: Pyrobaculum aerophilum; Pyrobaculum; Thermoproteaceae; Thermoproteales; Crenarchaeota; Archaea General Information: This organism was isolated from a boiling marine water hole in Maronti Beach, Ischia, Italy. It grows optimally a 100ºC and pH 7.0. Growth can occur at temperatures between 74 and 104 ºC. Nitrate-reducing hyperthermophilic archeon. This organism is a facultatively anaerobic, nitrate-reducing hyperthermophilic archaeon. It is able to grow both aerobically and anaerobically by dissimilatory nitrate reduction.
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General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.