Pre_GI: SWBIT SVG BLASTP

Query: NC_003155:5987000 Streptomyces avermitilis MA-4680, complete genome

Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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BLASTP Alignment.txt

Subject: NC_008609:708886 Pelobacter propionicus DSM 2379, complete genome

Lineage: Pelobacter propionicus; Pelobacter; Pelobacteraceae; Desulfuromonadales; Proteobacteria; Bacteria

General Information: Common environmental anaerobe. The genus Pelobacter encompasses a unique group of fermentative microorganisms in the delta-proteobacteria. This species is ubiquitous in both marine and fresh water, and in anaerobic sedmiments. It is able to convert the unsaturated hydrocarbon acetylene to to acetate and ethanol via acetylaldehyde as an intermediate. These microorganisms may survive in some sediments as an Fe(III) or elemental sulfur reducer as well as growing fermentatively as an ethanol-oxidizing acetogen.