Pre_GI: SWBIT SVG BLASTP

Query: NC_003155:5302280 Streptomyces avermitilis MA-4680, complete genome

Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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BLASTP Alignment.txt

Subject: NC_015564:4727630 Amycolicicoccus subflavus DQS3-9A1 chromosome, complete genome

Lineage: Amycolicicoccus subflavus; Amycolicicoccus; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Oil pollution has become a global issue because of its severe ecological impact and destruction. Bioremediation is proved to be an effective process to restore the oil polluted environments. Bacteria from oil contaminated environment always have the abilities for degradation of hydrocarbons and are thought to be useful in bioremediation of oil pollution. Amycolicicoccus subflavus DQS-9A1T, an actinomycete, is a type strain of newly published novel species in the novel genus Amycolicicoccus, isolated from the crude oil-polluted saline soil in China. The complete genome sequence of Amycolicicoccus subflavus DQS-9A1 will provide new strategies for bioremediation of oil contaminated environment.