Pre_GI: SWBIT SVG BLASTP

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTP Alignment.txt

Subject: NS_000195:1257834 Candidatus Cloacamonas acidaminovorans

Lineage: Cloacimonas acidaminovorans; Cloacimonas; ; ; unclassified Bacteria; Bacteria

General Information: Syntrophic bacterium that is present in many anaerobic digesters. The sludge sample was obtained from an anaerobic mesophilic digester (7,000 m3) at the Evry wastewater treatment plant (250,000 population equivalents), located about 35 km south of Paris, France.