Pre_GI: SWBIT SVG BLASTP

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTP Alignment.txt

Subject: NC_014221:266638 Truepera radiovictrix DSM 17093 chromosome, complete genome

Lineage: Truepera radiovictrix; Truepera; Trueperaceae; Deinococcales; Deinococcus-Thermus; Bacteria

General Information: Isolation: Water sample from a hot spring runoffs; Country: Portugal; Temp: Thermophile; Temp: 50C; Habitat: Fresh water, Hot spring. Truepera radiovictrix is a radiation-resistant species was isolated from hot spring runoff on the Island of Sao Miguel in the Azores. The hot springs in this area discharge neutral to slightly alkaline water that may reach the boiling point. These strains form orange/red colonies, spherical-shaped cells, have an optimum growth temperature of about 50 degrees C, an optimum pH for growth between about 7.5 and 9.5, and do not grow at pH below 6.5 or above pH 11.2.