Pre_GI: SWBIT SVG BLASTP

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTP Alignment.txt

Subject: NC_009515:510121 Methanobrevibacter smithii ATCC 35061, complete genome

Lineage: Methanobrevibacter smithii; Methanobrevibacter; Methanobacteriaceae; Methanobacteriales; Euryarchaeota; Archaea

General Information: Methanobrevibacter smithii ATCC 35061 (DSM 861) (strain PS) was isolated from a sewage digester in Gainesville, Florida, USA. Sewage digester isolate. Human gut methanogen. Methanobrevibacter smithii can be isolated from anoxic environments such as anaerobic digesters, anaerobic soil and sediment, and the gastrointestinal tracts of humans, ruminants and other animals. This organism is the dominant archaeal symbiont found in the human gut.