Pre_GI: SWBIT SVG BLASTP

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTP Alignment.txt

Subject: NC_008818:1644223 Hyperthermus butylicus DSM 5456, complete genome

Lineage: Hyperthermus butylicus; Hyperthermus; Pyrodictiaceae; Desulfurococcales; Crenarchaeota; Archaea

General Information: This organism was isolated from the sea floor of a solfataric (volcanic area that gives off gas) environment with temperatures up to 112 degrees C at a depth of 9 m, off the shore of Sao Miguel Island, Azores. Hyperthermophilic sulfur-reducing archaeon. This bacterium is an extreme hyperthermophilic, anaerobic, sulfur-reducing archaeon. Grows optimally at 95-106 degress C, with a NaCl concentration of 17 g/l and a pH of 7.0.