Pre_GI: SWBIT SVG BLASTP

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

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BLASTP Alignment.txt

Subject: NC_008209:695269 Roseobacter denitrificans OCh 114, complete genome

Lineage: Roseobacter denitrificans; Roseobacter; Rhodobacteraceae; Rhodobacterales; Proteobacteria; Bacteria

General Information: The aerobic phototrophic bacteria are ubiquitous as plant symbionts, free-living in lakes and ocean surface waters, soils and even near deep sea hydrothermal vents. Marine bacterium capable of aerobic anoxygenic photosynthesis. This bacterium was first isolated from a marine sediment collected on the coast of Australia. This organism's PufC photosynthetic protein has been studied as a classical tetraheme cytochrome, as it has all four possible heme-binding motifs.