Pre_GI: SWBIT SVG BLASTP

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

Subject: NC_006370:768745 Photobacterium profundum SS9 chromosome 1, complete sequence

Lineage: Photobacterium profundum; Photobacterium; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Isolated at a depth of 2500 m from the Sulu Trough. High pressure tolerant bacterium. This bioluminescent genus was originally identified in 1878 in association with hake (a marine fish) in Cape Town, South Africa. This species was originally isolated from an amphipod homogenate enrichment from the Sulu Sea. It is a genetically tractable model system for studies of low temperature and high pressure adaptation, and has been used in studies of mono- and polyunsaturated fatty acid production under these conditions.