Pre_GI: SWBIT SVG BLASTP

Query: NC_003103:266013 Rickettsia conorii str. Malish 7, complete genome

Lineage: Rickettsia conorii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.

Subject: NC_008789:350650 Halorhodospira halophila SL1, complete genome

Lineage: Halorhodospira halophila; Halorhodospira; Ectothiorhodospiraceae; Chromatiales; Proteobacteria; Bacteria

General Information: Halorhodospira halophila SL1 was isolated from salt lake mud. Sulfur-oxidizing extreme halophile. This organism, formerly Ectothiorhodospira halophila is alkaliphilic, phototrophic, halophile. This is one of the most halophilic eubacteria known, and produces organic solutes such as glycine betaine, ectoine, and trehalose to balance the osmotic pressure. This organism oxidizes sulfide to sulfur, which is deposited outside the cell and further oxidized to sulfate. This organism also produces a blue light sensor called photoactive yellow protein which is involved in signal transduction.