Pre_GI: SWBIT SVG BLASTP

Query: NC_003030:1097625 Clostridium acetobutylicum ATCC 824, complete genome

Lineage: Clostridium acetobutylicum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated in 1924 from garden soil in Connecticut, USA, by E. Wyer and L. Rettger. It is one of the best studied solventogenic clostridia. Solvent-producing bacterium. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism is a benign saccharolytic and proteolytic soil bacterium capable of producing a number of organic solvents (solventogenic bacterium) through fermentation of various organic compounds. acetobutyricum were isolated by Chaim Weizman during the World War I and used to develop industrial starch-based acetone, butanol and ethanol fermentation processes.

Subject: NC_000912:107273 Mycoplasma pneumoniae M129, complete genome

Lineage: Mycoplasma pneumoniae; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: This strain is a clinical isolate from a patient with atypical pneumonia. This genus currently comprises more than 120 obligate parasitic species found in a wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucous membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invasion, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.