Query: NC_002978:4973 Wolbachia endosymbiont of Drosophila melanogaster, complete genome Lineage: Wolbachia endosymbiont of Drosophila melanogaster; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria General Information: Wolbachia endosymbiont of Drosophila melanogaster. Fruitfly endosymbiont. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic or other type of relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission. Wolbachia endosymbiont of Drosophila melanogaster is an obligate intracellular endosymbiont of the fruit fly Drosophila melanogaster.
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General Information: This strain was isolated in the USA from the soft tick Ornithodoros turicatae. Borrelia turicatae is the causative agent of tick-borne relapsing fever in the southwestern USA. Ticks become infected with Borrelia while feeding on an infected mammal, usually a rodent or squirrel. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the spirochete into a mammalian host through its infectious saliva. Relapsing fever is characterized by period of chills, fever, headache, and malaise, followed by an asymptomatic, followed by another episode of symptoms. The cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.