Query: NC_002929:3305682 Bordetella pertussis Tohama I, complete genome Lineage: Bordetella pertussis; Bordetella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria General Information: This strain was originally isolated from a patient with whooping cough and has been studied extensively for over 40 years. Causative agent of whooping cough. This group of organisms is capable of invading the respiratory tract of animals and causing severe diseases. They express a number of virulence factors in order to do this including filamentous hemagglutins for attachment, cytotoxins, and proteins that form a type III secretion system for transport of effector molecules into host cells. This organism, which is unable to persist in the environment, is a strict human pathogen that causes whooping cough. Once a common cause of death in children the development of a vaccine has greatly decreased the number of deaths due to Bordetella pertussis. However, this organism infects and estimated 39 million people and kills hundreds of thousands of people each year.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This green-sulfur bacterium is a thermophile and was isolated from a New Zealand high-sulfide hot spring. Photosynthetic thermophile. Chlorobium tepidum is a member of the green-sulfur bacteria. It has been suggested that the green-sulfur bacteria were among the first photosynthetic organisms since they are anaerobically photosynthetic and may have arisen early in the Earth's history when there was a limited amount of oxygen present. This organism utilizes a novel photosynthetic system, and harvests light energy using an unusual organelle, the chlorosome, which contains an aggregate of light-harvesting centers surrounded by a protein-stabilized galactolipid monolayer that lies at the inner surface of the cytoplasmic membrane. Unlike many other photosynthetic organisms, the green-sulfur bacteria do not produce oxygen and tolerate only low levels of the molecule. This organism also fixes carbon dioxide via a reverse tricarboxylic acid cycle, using electrons derived from hydrogen or reduced sulfur to drive the reaction, instead of via the Calvin cycle like many other photosynthetic organisms.