Query: NC_002771:606491 Mycoplasma pulmonis UAB CTIP, complete genome Lineage: Mycoplasma pulmonis; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: Causes pneumonia-like disease in mice. This genus currently comprises more than 120 obligate parasitic species found in a wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucous membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invasion, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.
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General Information: This bacterium causes a contagious disease of cattle causing respiratory disease, mastitis, and arthritis. It is found worldwide and is inherently resistant to certain groups of antibiotics because it does not possess a cell wall. More recently, this species has become resistant to tetracycline, tilmicosin and spectinomycin which have been traditionally used in its control. The disease is spread between herds by the transfer of infected but seemingly healthy animals which shed viruses. It has also been introduced into healthy herds via frozen semen collected from an infected bull. The economic losses and negative impact on international trade from this disease have been considerable, and efforts are now underway to develop a vaccine.