Pre_GI: SWBIT SVG BLASTP

Query: NC_002745:572959 Staphylococcus aureus subsp. aureus N315, complete genome

Lineage: Staphylococcus aureus; Staphylococcus; Staphylococcaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain is a methicillin-resistant (MRSA) strain isolated in 1982 from a pharyngeal smear of a Japanese patient. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.

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Subject: NC_002620:705075 Chlamydia muridarum Nigg, complete genome

Lineage: Chlamydia muridarum; Chlamydia; Chlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: This is a wild-type strain that is virulent in mice. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. This organism causes pneumonitis (inflammation of lung tissue) in the mouse animal model and is used as a model organism to study pathogenesis.