Query: NC_002695:4153394 Escherichia coli O157:H7 str. Sakai, complete genome Lineage: Escherichia coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: This strain of O157:H7 was isolated in a 1997 outbreak in Sakai, Japan. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.
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General Information: This organism is the obligate endosymbiont for the tsetse fly Glossina brevipalpis. As Wigglesworthia brevipalpis resides intracellularly, the resulting co-evolution with its host over millions of years has led to a drastic reduction in the bacterium's genome size, resulting in this its inability to survive outside the host. Tsetse fly endosymbiont. This organism is the obligate endosymbiont for the tsetse fly Glossina brevipalpis, Glossina tachinoides, Glossina palpalis palpalis, and Glossina austeni. The tsetse fly is a vector for African trypanosomes, and is the main transmitter of deadly diseases in animals and humans in Africa. The fly feeds on a restricted diet, exclusively consisting of vertebrate blood, and lacks certain metabolic compounds needed for survival and reproduction. To complement this lack in nutrients, the tsetse fly relies mainly on the intracellular bacterial symbiont, Wigglesworthia glossinidia for its viability and fecundity.