Query: NC_002678:2739829 Mesorhizobium loti MAFF303099, complete genome Lineage: Mesorhizobium loti; Mesorhizobium; Phyllobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Plant symbiont bacterium. This organism contains a symbiosis island that is responsible for symbiotic relationships with plants (lotus) which is similar to what is observed with other Rhizobia that form similar relationships with legumes. The bacterium enters root nodules and performs nitrogen-fixation for the plant cell while being provided with a protective environment to grow in. Nitrogen fixation and root nodule formation genes are carried on a symbiosis island.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta by Dr. David Bruce during an epidemic among British soldiers. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.