Query: NC_002678:2739829 Mesorhizobium loti MAFF303099, complete genome Lineage: Mesorhizobium loti; Mesorhizobium; Phyllobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Plant symbiont bacterium. This organism contains a symbiosis island that is responsible for symbiotic relationships with plants (lotus) which is similar to what is observed with other Rhizobia that form similar relationships with legumes. The bacterium enters root nodules and performs nitrogen-fixation for the plant cell while being provided with a protective environment to grow in. Nitrogen fixation and root nodule formation genes are carried on a symbiosis island.
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General Information: This strain (live vaccine strain) was created in the 1960's in the USA and provides protection against tularemia in animal models as well as in humans. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.