Query: NC_002570:126500 Bacillus halodurans C-125, complete genome
Lineage: Bacillus halodurans; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: Strain C-125 (JCM9153) was isolated in 1977 and is the most well studied alkaliphilic Bacillus organism. Alkaliphilic bacterium. This organism is similar to Bacillus subtilis but is alkaliphilic, grows poorly at neutral pH, and very well at pH >9.5. This bacterium produces a peptidoglycan that contains teichuronic peptides consisting of polyglutamic and polyglucuronic acids that counteract the halophilic environment.
Subject: NC_013316:1 Clostridium difficile R20291, complete genome
Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria
General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.