Query: NC_002162:138334 Ureaplasma parvum serovar 3 str. ATCC 700970, complete genome Lineage: Ureaplasma parvum; Ureaplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: This organism (Ureaplasma urealyticum biovar 1) is normally found as a commensal organism in the human genital tract. As an opportunistic pathogen, it can cause a sexually-transmitted disease and is recognized as causing non-chlamydial non-gonococcal urethritis. It can also cause obstetric complications in pregnant women, severe infections in infants, as well as meningitis. Like other Mollicutes, it is a wall-less bacterium and has undergone marked genome reduction. This organism appears to generate ATP through the hydrolysis of urea by the urease enzyme.
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General Information: This biovar nodulates legumes in the Tribe Viciae (Vicia, Pisum, Lathyrus, Lens). This strain is a spontaneous streptomycin-resistant mutant of strain 300. Nitrogen-fixing plant symbiont. This organism, like other Rhizobia, establishes a symbiotic relationship with a legume plant, providing nitrogen in exchange for a protected environment. The legume roots secrete flavonoids and isoflavonoids which the bacteria recognize and use to turn on genes involved in root nodulation. Many of the root nodulation genes are involved in synthesis and secretion of a nodule inducing signal, a lipochito-oligosaccharide molecule, which the plant recognizes, triggering nodule formation. The bacterium is endocytosed and exists inside a membrane bound organelle, the symbiosome, and fixes nitrogen for the plant cell while the host cell provides carbon compounds for the bacterium to grow on. The nitrogen fixation is important as it obviates the need for expensive and environmentally damaging fertilizer use.