Query: NC_000963:141500 Rickettsia prowazekii str. Madrid E, complete genome Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.
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General Information: Aeromonas veronii is a Gram-negative, rod-shaped bacterium found in fresh water and in association with animals. It can be a pathogen of humans and a beneficial symbiont of leeches. In humans A. veronii can cause diseases ranging from wound infections and diarrhea to septicemia in immunocompromised patients. In leeches, this bacterium is thought to function in the digestion of blood, provision of nutrients or preventing other bacteria from growing.