Query: NC_000908:160072 Mycoplasma genitalium G37, complete genome Lineage: Mycoplasma genitalium; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: This strain was isolated as a urethral specimen from a male patient with nongonococcal urethritis. This genus currently comprizes more than 120 obligate parasitic species found in the wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucouse membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invation, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most of mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.
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General Information: This strain was isolated from a sample of coastal sea water near a French Antarctic station. This organism is adapted to growth at low temperatures and reactive oxygen species by a number of putative dioxygenases and fatty acid desaturases amongst other proteins. The organism can grow optimally in salt concentrations of 1.5 to 3.5% NaCl.The genome consists of 2 chromosomes, one of which may replicate unidirectionally. Some interesting features of this genome include the lack of the nucleoid-associated gene hns, a lack of genes involved in molybdopterin metabolism, a lack of the cAMP-CAP complex, and a lack of the PEP-dependent PTS system.