Query: NC_020419:344000 Uncultured Termite group 1 bacterium phylotype Rs-D17 DNA, complete
Lineage: uncultured Termite group 1 bacterium; enviromental sample; ; ; Elusimicrobia; Bacteria
General Information: The Termite Group 1 (TG1) bacteria are a dominant group in termite guts, where they are part of the symbiotic microbial community that is required for the termite to thrive. The TG1 bacteria are found as intracellular symbionts of various cellulolytic protists.
Subject: NC_010263:925500 Rickettsia rickettsii str. Iowa, complete genome
Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.