Query: NC_020411:1232962 Hydrogenobaculum sp. HO, complete genome
Lineage: Hydrogenobaculum; Hydrogenobaculum; Aquificaceae; Aquificales; Aquificae; Bacteria
General Information: Environment: Fresh water; Temp: Thermophile; Temp: 58. Isolated from Yellowstone National Park.
Subject: NC_008343:823093 Granulibacter bethesdensis CGDNIH1, complete genome
Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.