Query: NC_020272:3706722 Bacillus amyloliquefaciens IT-45, complete genome Lineage: Bacillus amyloliquefaciens; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Bacillus amyloliquefaciens is a member of a group of free-living soil bacteria known to promote plant growth and suppress plant pathogens. Bacillus amyloliquefaciens is able to degrade myo-inositol hexakisphosphate (phytate), making phosphorus more available to plants. This organism also produces antifungal and antibacterial substances, such as bacillomycin D, surfactin, and bacillaene, which protect the plant from pathogenic organisms. In addition, proteases and amylases produced by Bacillus amyloliquefaciens are used in industrial applications.
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General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.