Query: NC_020133:2886541 Mycobacterium liflandii 128FXT, complete genome Lineage: Mycobacterium liflandii; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria General Information: First isolated from a colony of African clawed frogs. This organism causes a fatal systemic disease in frogs often characterized by skin lesions. Mycobacterium liflandii produces a polyketide toxin mycolactone E and two highly antigenic proteins ESAT-6 and CFP-10 which account, in part, for its pathogenicity.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.