Query: NC_019892:7822000 Singulisphaera acidiphila DSM 18658 chromosome, complete genome Lineage: Singulisphaera acidiphila; Singulisphaera; Planctomycetaceae; Planctomycetales; Planctomycetes; Bacteria General Information: Country: Russia; Environment: Acidic wetlands; Isolation: Sphagnum peat sampled from the bog; Temp: Mesophile; Temp: 20-26C. Singulisphaera acidiphila is a member of the planctomyces which are commonly isolated from aquatic and terrestrial environments. This bacterium was originally isolated from a peat bog and is moderately acidophilic.
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General Information: This strain was isolated from an infected goat and is pathogenic in humans. Causes brucellosis and undulant fever. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.