Pre_GI: SWBIT SVG BLASTN

Query: NC_017516:917817 Neisseria meningitidis H44/76 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTN Alignment.txt

Subject: NC_007973:2773427 Ralstonia metallidurans CH34 chromosome 1, complete sequence

Lineage: Cupriavidus metallidurans; Cupriavidus; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain was first identified in the heavy metal-contaminated sludge of a settling tank in Belgium in the late 1970s. This organism, formerly Ralstonia metallidurans, is capable of growth in the presence of a large number of heavy metals including silver, cadmium, chromium, cobalt, copper, mercury, nickel, lead, thallium, and zinc.