Pre_GI: SWBIT SVG BLASTN

Query: NC_017516:1408000 Neisseria meningitidis H44/76 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_008825:1258500 Methylibium petroleiphilum PM1, complete genome

Lineage: Methylibium petroleiphilum; Methylibium; ; Burkholderiales; Proteobacteria; Bacteria

General Information: Methylibium petroleiphilum strain PM1 (ATCC BAA-1232) was isolated in 1998 from the biofilter of a treatment plant in an oil refinery in Los Angeles, California, USA. Strain PM1 is capable of degrading aromatic compounds such as benzene, toluene and xylenes. Methyl tertiary-butyl ether-degrading bacterium. Methylibium petroleiphilum is a methylotroph (able to utilize reduced one-carbon compounds) able to degrade methyl tertiary-butyl ether (MTBE) under aerobic conditions. MTBE is a gasoline additive used as an oxygenate and to raise the octane number.