Pre_GI: SWBIT SVG BLASTN

Query: NC_017512:2087098 Neisseria meningitidis WUE 2594, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_011059:2233993 Prosthecochloris aestuarii DSM 271, complete genome

Lineage: Prosthecochloris aestuarii; Prosthecochloris; Chlorobiaceae; Chlorobiales; Chlorobi; Bacteria

General Information: This species is a green sulfur bacterium which forms sedimentary biofilm layers. It has been shown to be associated with coral killed by Black-Band Disease (BBD) a microbial infection of larger coral species. This is a concern for reef conservationists as the larger species are responsible for coral scaffolds, and their reduction by disease would have considerable impact on the reef structure. While there is currently no cause-and-effect link between Prosthecochloris aestuarii and BBD, the species was found on coral which was killed by the disease and was not found on healthy coral or in the surrounding seawater.