Pre_GI: SWBIT SVG BLASTN

Query: NC_017512:2087098 Neisseria meningitidis WUE 2594, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_010524:4402478 Leptothrix cholodnii SP-6, complete genome

Lineage: Leptothrix cholodnii; Leptothrix; Comamonadaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Leptothrix cholodnii SP-6 was isolated from water and flocculent from an artificial iron seep in Ithaca, NY, USA. Leptothrix cholodnii, like other Leptothrix species is an iron- and manganese-oxidizing, sheathed bacterium common in organic rich aquatic environments. Iron oxides and manganese oxides often coat the sheathes of these organisms.