Pre_GI: SWBIT SVG BLASTN

Query: NC_017512:2087098 Neisseria meningitidis WUE 2594, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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Subject: NC_008751:2060391 Desulfovibrio vulgaris subsp. vulgaris DP4, complete genome

Lineage: Desulfovibrio vulgaris; Desulfovibrio; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria

General Information: A sulfate reducing bacterium. These organisms typically grow anaerobically, although some can tolerate oxygen, and they utilize a wide variety of electron acceptors, including sulfate, sulfur, nitrate, and nitrite. A number of toxic metals are reduced, including uranium (VI), chromium (VI) and iron (III), making these organisms of interest as bioremediators. Metal corrosion, a problem that is partly the result of the collective activity of these bacteria, produces billions of dollars in losses each year to the petroleum industry. These organisms are also responsible for the production of poisonous hydrogen sulfide gas in marine sediments and in terrestrial environments such as drilling sites for petroleum products. This species is a sulfate reducer commonly found in a variety of soil and aquatic environments.