Pre_GI: SWBIT SVG BLASTN

Query: NC_017511:602000 Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genome

Lineage: Neisseria gonorrhoeae; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.

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BLASTN Alignment.txt

Subject: NC_010939:1633000 Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete

Lineage: Actinobacillus pleuropneumoniae; Actinobacillus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Actinobacillus pleuropneumoniae serovar 7 str. AP76 is a clinical isolated from a pig lung. This organism is an obligate parasite of pigs. The bacterium colonizes and invades the porcine lower respiratory tract and can survive phagocytosis by macrophages, eventually resulting in the death of the macrophage cell. Three RTS toxins, which result in cell damage, are produced by this organism.