Pre_GI: SWBIT SVG BLASTN

Query: NC_017295:3300500 Clostridium acetobutylicum EA 2018 chromosome, complete genome

Lineage: Clostridium acetobutylicum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism is a benign saccharolytic and proteolytic soil bacterium capable of producing a number of organic solvents (solventogenic bacterium) through fermentation of various organic compounds. The first strains of C. acetobutyricum were isolated by Chaim Weizman during the World War I and used to develop industrial starch-based acetone, butanol and ethanol fermentation processes. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA.

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BLASTN Alignment.txt

Subject: NC_003869:14153 Thermoanaerobacter tengcongensis MB4, complete genome

Lineage: Caldanaerobacter subterraneus; Caldanaerobacter; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: This organism was originally isolated from a hot spring in Tengcong, China, and is the type strain for the species. Genomic analysis indicates it is similar to Bacillus halodurans and that it has one of the most biased leading strand distribution of genes. Although the organism has not been observed to be motile or to sporulate, it does contain genes for both functions. The bacterium produces acetate and ethanol from glucose and cannot degrade xylan and cellulose.