Query: NC_017249:7917586 Bradyrhizobium japonicum USDA 6, complete genome Lineage: Bradyrhizobium japonicum; Bradyrhizobium; Bradyrhizobiaceae; Rhizobiales; Proteobacteria; Bacteria General Information: This nitrogen-fixing bacterium develops a symbiotic relationship with the soybean plant Glycine max and is related to other N2-fixing Rhizobia which are symbiotic with legumes. The bacterium establishes itself in a root nodule which provides a protective environment for the organism to live while the bacterium provides the plant cell with nitrogen. This is an agriculturally important symbiotic relationship as it obviates the need for expensive and environmentally damaging fertilizer.Genes that code for proteins involved in root nodulation are carried on the chromosome. The production of the nodulation signal, lipochitin, is directed by genes which are turned on in the presence of plant flavonoid compounds. The bacteria are endocytosed into a cortical cell, and are enclosed within a membrane bound organelle termed the symbiosome.
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General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.