Query: NC_017249:7341428 Bradyrhizobium japonicum USDA 6, complete genome Lineage: Bradyrhizobium japonicum; Bradyrhizobium; Bradyrhizobiaceae; Rhizobiales; Proteobacteria; Bacteria General Information: This nitrogen-fixing bacterium develops a symbiotic relationship with the soybean plant Glycine max and is related to other N2-fixing Rhizobia which are symbiotic with legumes. The bacterium establishes itself in a root nodule which provides a protective environment for the organism to live while the bacterium provides the plant cell with nitrogen. This is an agriculturally important symbiotic relationship as it obviates the need for expensive and environmentally damaging fertilizer.Genes that code for proteins involved in root nodulation are carried on the chromosome. The production of the nodulation signal, lipochitin, is directed by genes which are turned on in the presence of plant flavonoid compounds. The bacteria are endocytosed into a cortical cell, and are enclosed within a membrane bound organelle termed the symbiosome.
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General Information: Etiologic agent of canine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This bacterium is the causative agent of canine brucellosis. The main sources of infection are vaginal fluids of infected females and urine in males. The most significant symptoms are late abortions in bitches, epididymitis in males and infertility in both sexes, as well as generalized lymphadenitis, discospondylitis and uveitis. Human contagion is not frequent, although it has been reported, and is easily treated. B. canis can be differentiated from the other species of the genus Brucella (except B. ovis) in that it forms rugose colonies.