Query: NC_017238:427482 Borrelia afzelii PKo chromosome, complete genome
Lineage: Borrelia afzelii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria
General Information: This species was isolated from a skin lesion from a Lyme disease patient in Europe in 1993. It is a specific aetological agent of acrodermatitis chronica atrophicans (ACA). This organism can be differentiated from other Borrelia species by monoclonal antibody hybridization.
Subject: NC_008513:343540 Buchnera aphidicola str. Cc (Cinara cedri), complete genome
Lineage: Buchnera aphidicola; Buchnera; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This strain is found in the cedar aphid, Cinara cedri. Aphid endosymbiont. Almost all aphids contain maternally transmitted bacteriocyte cells, which themselves contain bacteria called Buchnera. The aphids live on a restricted diet (plant sap), rich in carbohydrates, but poor in nitrogenous or other essential compounds. It is believed that the Buchnera provide the essential nutrients the host lacks. Besides a nutritional co-dependence, due to a co-existence of millions of years, Buchnera have lost the ability to produce cell surface components such as lipopolysaccharides. This makes for an obligate endosymbiont relationship between host and Buchnera. Buchnera are prokaryotic cells which belong to the gamma-Proteobacteria, closely related to the Enterobacteriaceae family. Phylogenetic studies using 16S rRNA indicate that the symbiotic relationship was established around 200-250 million years ago. Since Buchnera are closely related to Escherichia coli and Haemophilus influenzae, comparative genomic studies can shed light on the evolutionary mechanisms of intracellular endosymbiosis as well as the different underlying molecular basis between organisms with parasitic behavior and symbionts.