Query: NC_017218:2119964 Bifidobacterium breve ACS-071-V-Sch8b chromosome, complete genome Lineage: Bifidobacterium breve; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. This organism is one of the first colonizers of the human gastrointestinal tract, and is a dominant member of the adult intestinal microbial community. Probiotics are live microbial supplements which benefit the health of an animal by maintaining normal microbial flora, producing vitamins, and stimulating the mucosal immune system
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General Information: Originally identified as Pseudomonas sp. LB400 that was found in contaminated soil in upstate New York, USA, this organism is now classified in the genus Burkholderia. Polychlorinated biphenyl-degrading bacterium. Member of the genus Burkholderia are versatile organisms that occupy a surprisingly wide range of ecological niches. These bacteria are exploited for biocontrol, bioremediation, and plant growth promotion purposes. Burkholderia xenovorans has been found on fungi, animals, and from human clinical isolates such as from cystic fibrosis (CF) patients. It may be tightly associated with white-rot fungus, as the degadation of lignin by the fungus results in aromatic compounds the bacterium can then degrade. This organism is exceptionally capable of degradation of polychlorinated biphenyls (PCBs), which are environmental pollutants, and thus it may play a role in bioremediation of polluted and toxic sites and is studied as a model bioremediator. PCBs can be utilized as the sole carbon and energy source by this organism. The pathways for degradation of PCBs have been extensively characterized at both the genetic and the molecular level and have become a model system for the bacterial breakdown of these very persistent environmental contaminants.