Pre_GI: SWBIT SVG BLASTN

Query: NC_017218:2223604 Bifidobacterium breve ACS-071-V-Sch8b chromosome, complete genome

Lineage: Bifidobacterium breve; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. This organism is one of the first colonizers of the human gastrointestinal tract, and is a dominant member of the adult intestinal microbial community. Probiotics are live microbial supplements which benefit the health of an animal by maintaining normal microbial flora, producing vitamins, and stimulating the mucosal immune system

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Subject: NC_012804:1940500 Thermococcus gammatolerans EJ3, complete genome

Lineage: Thermococcus gammatolerans; Thermococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea

General Information: Hyperthermophilic radioresistant marine archaeon. Thermococcus gammatolerans was isolated from hydrothermal vent chimneys located in the mid-Atlantic Ridge and Guyamas basin. When exposed to gamma radiation, this organism has a survival curve similar to Deinococcus radiodurans.