Pre_GI: SWBIT SVG BLASTN

Query: NC_017218:2119964 Bifidobacterium breve ACS-071-V-Sch8b chromosome, complete genome

Lineage: Bifidobacterium breve; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. This organism is one of the first colonizers of the human gastrointestinal tract, and is a dominant member of the adult intestinal microbial community. Probiotics are live microbial supplements which benefit the health of an animal by maintaining normal microbial flora, producing vitamins, and stimulating the mucosal immune system

Subject: NC_007347:767455 Ralstonia eutropha JMP134 chromosome 1, complete sequence

Lineage: Cupriavidus pinatubonensis; Cupriavidus; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This organism is found in both soil and water and has great potential for use in bioremediation as it is capable of degrading a large list of pollutants including chlorinated aromatic compounds. The bacterium can utilize hydrogen, carbon dioxide, as well as organic compounds for growth and is a model organism for hydrogen oxidation as it can grow on hydrogen as the sole energy source. It was originally isolated due to its ability to degrade the herbicide 2,4-dichlorophenoxyacetic acid, which is due to the degradative functions being encoded on a plasmid (pJP4). Metabolically versatile bacterium. Cupriavidus necator also known as Ralstonia eutropha is a soil bacterium with diverse metabolic abilities. Strains of this organism are resistant to high levels of copper or are able to degrade chloroaromatic compounds such as halobenzoates and nitrophenols making them useful for bioremediation.