Pre_GI: SWBIT SVG BLASTN

Query: NC_017200:5325977 Bacillus thuringiensis serovar finitimus YBT-020 chromosome,

Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis.

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BLASTN Alignment.txt

Subject: NC_004344:672550 Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,

Lineage: Wigglesworthia glossinidia; Wigglesworthia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the obligate endosymbiont for the tsetse fly Glossina brevipalpis. As Wigglesworthia brevipalpis resides intracellularly, the resulting co-evolution with its host over millions of years has led to a drastic reduction in the bacterium's genome size, resulting in this its inability to survive outside the host. Tsetse fly endosymbiont. This organism is the obligate endosymbiont for the tsetse fly Glossina brevipalpis, Glossina tachinoides, Glossina palpalis palpalis, and Glossina austeni. The tsetse fly is a vector for African trypanosomes, and is the main transmitter of deadly diseases in animals and humans in Africa. The fly feeds on a restricted diet, exclusively consisting of vertebrate blood, and lacks certain metabolic compounds needed for survival and reproduction. To complement this lack in nutrients, the tsetse fly relies mainly on the intracellular bacterial symbiont, Wigglesworthia glossinidia for its viability and fecundity.