Pre_GI: SWBIT SVG BLASTN

Query: NC_017168:3535786 Yersinia pestis A1122 chromosome, complete genome

Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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BLASTN Alignment.txt

Subject: NC_014221:266638 Truepera radiovictrix DSM 17093 chromosome, complete genome

Lineage: Truepera radiovictrix; Truepera; Trueperaceae; Deinococcales; Deinococcus-Thermus; Bacteria

General Information: Isolation: Water sample from a hot spring runoffs; Country: Portugal; Temp: Thermophile; Temp: 50C; Habitat: Fresh water, Hot spring. Truepera radiovictrix is a radiation-resistant species was isolated from hot spring runoff on the Island of Sao Miguel in the Azores. The hot springs in this area discharge neutral to slightly alkaline water that may reach the boiling point. These strains form orange/red colonies, spherical-shaped cells, have an optimum growth temperature of about 50 degrees C, an optimum pH for growth between about 7.5 and 9.5, and do not grow at pH below 6.5 or above pH 11.2.