Query: NC_017167:1405626 Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1 Lineage: Alicyclobacillus acidocaldarius; Alicyclobacillus; Alicyclobacillaceae; Bacillales; Firmicutes; Bacteria General Information: Alicyclobacillus acidocaldarius, formerly Bacillus acidocaldarius was first isolated from an acidic creek in Yellowston National Park and grows at a pH of 3.6. This organism is both thermophilic and acidophilic and produces heat and acid stable enzymes, such as amylase and esterase, which may be important in industry.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.