Query: NC_017138:980696 Bacillus megaterium WSH-002 chromosome, complete genome Lineage: Bacillus megaterium; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Bacillus megaterium is a naturally occurring soil bacterium, originally named because of its large size in relation to E. coli. This bacterium produces a number of useful enzymes, such as, amylases and proteases which have industrial uses. In addition this organism can be used for the production and export of other economically important compounds.
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General Information: This strain was isolated in Canada during a study of cheese spoilage. Soil microorganism that can cause food poisoning. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.