Pre_GI: SWBIT SVG BLASTN

Query: NC_017062:61500 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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BLASTN Alignment.txt

Subject: NC_015144:734726 Weeksella virosa DSM 16922 chromosome, complete genome

Lineage: Weeksella virosa; Weeksella; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria

General Information: Environment: Host; Isolation: Human urine; Temp: Mesophile; Country:USA: North Carolina. Weeksella virosa is a nonsaccharolytic, oxidase- and catalase-positive, gram-negative rod. It has been isolated mainly from the female genitourinary tract.