Pre_GI: SWBIT SVG BLASTN

Query: NC_017062:61500 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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BLASTN Alignment.txt

Subject: NC_009613:1337536 Flavobacterium psychrophilum JIP02/86, complete genome

Lineage: Flavobacterium psychrophilum; Flavobacterium; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria

General Information: Flavobacterium psychrophilum JIP02/86 (ATCC 49511) is a virulent strain. Flavobacterium psychrophilum cause cold water disease in salmon and trout. This bacterium causes septicemia in young fish (rainbow trout fry syndrome) and extensive lesions in adult fish. There is a high rate of mortality associated with these diseases with considerable economic impact for the aquaculture industry.