Pre_GI: SWBIT SVG BLASTN

Query: NC_017062:33268 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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BLASTN Alignment.txt

Subject: NC_008618:1804610 Bifidobacterium adolescentis ATCC 15703, complete genome

Lineage: Bifidobacterium adolescentis; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria

General Information: Human gut bacterium. This species is a normal inhabitant of the healthy human gut. Newborns, especially those that are breast-fed, are colonized with Bifidobacteria within days after birth. This species was first isolated from the feces of a breast-fed infant. In one comprehensive 16S rDNA sequence-based enumeration of the colonic microbiota of three healthy adult humans it represents, on average, 0.008% of all 16S rDNA sequences and 4.302% of the sequences in its division (Eckburg et. They are saccharolytic organisms that produce acetic and lactic acids without generation of CO2, except during degradation of gluconate.