Query: NC_017058:497500 Rickettsia australis str. Cutlack chromosome, complete genome Lineage: Rickettsia australis; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Animal pathogen in Mammalia (intracellular obligate). Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Rickettsia australis causes a medical condition called Queensland tick typhus. The probable vectors are the tick species, Ixodes holocyclus and Ixodes tasmani. Small marsupials are suspected reservoirs of this bacterium.
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General Information: This strain was obtained from an infected tick and maintained by serial infection in mice. Obligate intracellular bacterium and causative agent of heartwater. This organism causes heartwater, a disease with a high mortality rate that affects both wild and domesticated ruminants in sub-Saharan Africa and parts of the Caribbean. The name heartwater refers to the hydropericardium (excessive fluid in the sac surrounding the heart) commonly found associated with infection. This organism is found in membrane-bound vacuoles in endothelial cells and neutrophils and is an obligate intracellular parasite.