Query: NC_017027:1329708 Pasteurella multocida subsp. multocida str. HN06 chromosome, Lineage: Pasteurella multocida; Pasteurella; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria General Information: This organism was one of the first pathogens ever sudied, and is named after Louis Pasteur, who used it in his vaccination studies in the 1880s. This organism usually resides in the mucous membranes of the intestinal, genital, and respiratory tissues and is an opportunistic pathogen that causes cholera in fowl, bovine hemorrhagic septicemia, and porcine atrophic rhinitis. Collectively these diseases cause millions of dollars in lost livestock every year. The organism can also infect humans if they are bitten by dogs and cats, which are carriers of the organism, but which are asymptomatic. This organism also expresses a hydrophilic capsule that inhibits phagocytosis and complemented-mediated attack.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Soil microorganism that can cause food poisoning. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. There are two forms of food poisoning that occur, one is rapid onset (emetic) and the other is late onset (diarrheal). The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.